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How To Get Polyunsaturated Fatty Acids Out Of The Body

By Christopher Walker

How To Get Polyunsaturated Fatty Acids Out Of The Body
  • DISCLAIMER: Dietary suggestions contained in this blog post are based on the Thermogenic lifestyle. Not all dietary suggestions are suitable for each individual.  Please consult your healthcare professional before making any changes to your dietary or supplement routine.

    Research on polyunsaturated fatty acids (PUFAs) has indicated that they may have varying effects on health and metabolism. While some discussions on metabolism have suggested that carbohydrates, including sugar, can be beneficial for metabolism, the effects of different types of fats are still being studied.

    Some studies have linked high intake of PUFAs to potential negative effects on health and metabolism. However, It is important to note that the relationship between dietary factors and health outcomes is complex. In this article, we are investigating the history of PUFAs, their potential effects on health and metabolism, and how to avoid them.

    Table Of Contents:

    Why Does The Mainstream Believe PUFA Are Healthy?

    How To Fatten Up Livestock With Less Food

    What Are Fatty Acids?

    The Damaging Effects Of Polyunsaturated Fatty Acids

    Nature Gives Us Clues

    The Detoxification Of Polyunsaturated Fatty Acids

    But Aren't the "Essential Fatty Acids" Unsaturated?

    The Metabolic Power Of Shorter Chain Fats

    Fatty Acid Recommendations

    Key Points




The Mainstream View on PUFAs and Health: A Historical Perspective

why the mainstream thinks pufas are good

The mainstream belief that polyunsaturated fatty acids (PUFAs) are healthy can be traced back to early research and marketing efforts that promoted their potential benefits. However, the relationship between cholesterol and health has since been reevaluated, and some studies have linked low cholesterol levels to increased health risks.

It is worth noting that PUFAs are known to be unstable and oxidize easily, which can cause the production of free radicals. Since PUFAs lead to free radicals in the body, they might contribute to oxidative stress, potentially affecting metabolism and cellular energy production. However, the full extent of these effects is still debated, and more research is needed to provide a clearer understanding of PUFAs' role in health and metabolism.

One historical quote from Dr. Broda Barnes highlights the controversy surrounding PUFAs, though it is important to keep in mind that this quote reflects an individual opinion and not a consensus among experts:

"Polyunsaturated fats offer you absolutely nothing except an earlier grave.  This is a fake. Polyunsaturated fats, when this story is finally written, are going to make Watergate look like a church social. This is a lie that has been forced on the public. Originally, they were in earnest. They thought it was true. But they know better today." - Dr. Broda Barnes


As our understanding of nutrition and metabolism evolves, it is essential to stay informed about the latest research and consider a variety of perspectives before making decisions about dietary choices and health.




A Historical Perspective on Livestock Fattening Practices

how to fatten up livestock with less food

In the past, farmers have explored various approaches to increase the size of their livestock while minimizing feed costs. One approach was to experiment with different types of fats in the animals' diets, with the goal of altering their metabolic rates to promote weight gain.

In the 1940s, farmers initially tried using coconut oil, a natural source of saturated fat, to fatten up their livestock. However, this approach did not yield the desired results. Farmers then considered the use of an anti-thyroid drug to affect the animals' metabolism, but this option was later found to be potentially harmful due to its carcinogenic properties.

Another approach explored by farmers involved incorporating polyunsaturated fats from vegetable oils into the animals' diets. Some historical accounts suggest that this method was more successful in promoting weight gain in livestock. While the metabolic processes of animals can differ significantly from humans, it is interesting to find that PUFAs have historically been used to promote weight gain in livestock.

To better understand the potential impact of polyunsaturated fatty acids (PUFAs) on health and metabolism, it is essential to consider the latest research findings and maintain a balanced perspective on dietary fats.




Understanding Fatty Acids: An Overview

what are fatty acids

Fatty acids are essential components of dietary fats and play various roles in the body. They consist of a carboxyl group attached to a chain of carbon atoms, with the chain length and bond types being key characteristics that differentiate them.

Saturated fats have carbon molecules bound to the maximum number of hydrogens, whereas unsaturated fats have fewer hydrogens due to the presence of double bonds between carbon atoms. Monounsaturated fatty acids (MUFAs) have one double bond, while polyunsaturated fatty acids (PUFAs) have two or more double bonds.

It is important to note that these double bonds in unsaturated fats can make them more susceptible to oxidation when exposed to heat, light, or oxygen, potentially leading to the formation of free radicals. Free radicals can cause damage by attacking other molecules to steal an electron, initiating a chain reaction that can be stopped by antioxidants, such as vitamins E and C. Unsaturated fats, particularly PUFAs, are generally more reactive than saturated fats due to their multiple double bonds, which may be a point of concern for some researchers.




For a step by step guide on how to eat to avoid these toxic fats and promote overall health of the body, make sure to check out The Thermo Diet inside of UMZUfit!

the thermo diet




Potential Effects of Polyunsaturated Fatty Acids on Metabolism: A Review of Research Findings

the damaging effects of pufas

Research on the impact of polyunsaturated fatty acids (PUFAs) on metabolism has produced varying results. Some studies have suggested that PUFAs may affect the function of the mitochondria, the cell's energy-generating components.

Mitochondria play a crucial role in meeting the body's energy demands. When they are unable to do so, cells may shift to a stress metabolism state, leading to increased anaerobic glycolysis and the production of lactic acid instead of CO2. Unsaturated fats, including PUFAs, can also be metabolized by the mitochondria. However, there have been concerns raised about the potential for unsaturated fats to oxidize when exposed to the high levels of oxygen and heat present in the mitochondria, leading to the formation of free radicals that could damage the mitochondria and reduce energy production.

On the other hand, saturated fats are considered more stable due to their lack of double bonds, and some studies have suggested that they may be metabolized without generating harmful free radicals.



Nature's Adaptations to Fatty Acids in Various Environments

nature tells us the way

When observing the natural world, we can see that organisms have evolved to use different types of fats depending on their environment. Saturated fats are typically solid at room temperature, while unsaturated fats are liquid. The number of double bonds in fat affects its melting point.

For example, monounsaturated fats like olive oil have a melting point of around 22 degrees F, whereas highly unsaturated fish oils found in cold-water fatty fish like salmon have melting points as low as -50 to -60 degrees F. The melting point of fats is important because it allows plants and animals to function optimally in their specific environments.

In cold climates, organisms rely on unsaturated fats to maintain fluidity and avoid stiffening. In warmer climates, saturated fats like coconut oil are more prevalent, as they can resist peroxidation at higher temperatures. This adaptation helps prevent damage to tropical plants that are exposed to high heat.

It is interesting to consider these evolutionary adaptations when discussing dietary fats for human consumption. However, it is important to recognize that the relationship between dietary fats and human health is complex and not solely based on the natural occurrence of these fats in various organisms and environments. To make informed choices about dietary fats, it is crucial to consult with healthcare professionals and consider the latest research on the topic.



The Gradual Reduction of Polyunsaturated Fatty Acids: A Look at Current Research

detoxification of pufas

Some researchers have suggested that it may be beneficial to prioritize the consumption of saturated fats while minimizing the intake of unsaturated fats, particularly polyunsaturated fatty acids (PUFAs). One reason for this suggestion is the potential for PUFAs to contribute to oxidative stress and free radical production in the body.

However, it is important to note that the body stores various types of fats, including PUFAs, in its fat stores. Some studies have estimated that the half-life of fat stores is around 400-600 days, which means that it could take up to 2-3 years to gradually reduce the number of PUFAs in the body.

Increasing saturated fat intake may help in managing the release of stored PUFAs, potentially minimizing oxidative stress and free radical production. Some research has also suggested that consuming higher amounts of saturated fats, such as coconut oil, could help protect against the potential negative effects of PUFAs.

It is essential to consider the complex relationship between dietary fats and human health when making decisions about fat intake. Healthcare professionals should always be consulted, and the latest research on the topic should be taken into account. Additionally, it is important to ensure adequate intake of antioxidants, such as vitamin E, which can play a role in protecting against potential damage from PUFAs.


A Look at Current Research on Unsaturated Fatty Acids and Essential Fatty Acids

essential fatty acids

There has been ongoing debate and research regarding essential fatty acids (EFAs) and their role in human health. Some studies have suggested that increasing the intake of specific B vitamins and minerals may help alleviate the perceived need for EFAs. This research indicates that the body may be able to generate certain unsaturated fats, such as Mead acid, in the absence of EFAs.

Mead acid has been found to have anti-inflammatory properties and may provide some health benefits. However, more research is needed to understand its full effects on human health, and whether it can be considered an alternative to traditionally recognized EFAs, such as omega-3 fatty acids.

It is essential to consider the complex relationship between dietary fats and human health when making decisions about fat intake. Healthcare professionals should always be consulted, and the latest research on the topic should be taken into account. As the understanding of EFAs and their role in the body continues to evolve, it is crucial to stay informed about new findings and their potential implications for overall health.

The Metabolic Power Of Shorter-Chain Fats

the power of shorter chain fatty acids

Before we delve into specific recommendations, there's one more important point to consider. Do you remember when we discussed the different lengths of carbon chains in fatty acids?

Well, it turns out that short- and medium-chain fatty acids behave differently than long-chain fats, both in terms of digestion and utilization. Firstly, they bypass being packaged into triglycerides, like long-chain fats, and instead go directly to the liver, much like fructose.

Once inside the cell, short- and medium-chain fats do not require the carnitine-transport system that long-chain fats do. This means they can be rapidly absorbed into the mitochondria of the cell, where they form acetyl-CoA, a critical molecule for initiating the aerobic respiration pathway.

Research has suggested that these short- and medium-chain fats may have pro-metabolic and inflammation-reducing effects. This is a significant reason why coconut oil is thought to be effective in boosting metabolism, as it is predominantly made up of short- and medium-chain fatty acids.

Moreover, extremely short-chain fats such as butyric acid, propanoic acid, and acetic acid are believed to possess potent anti-inflammatory properties.  By incorporating more of these fatty acids into the diet, cells may activate aerobic pathways, similar to fructose, but through a different mechanism.



Fatty Acid Recommendations

fatty acid recommendations




  1. Avoid all polyunsaturated fats: This includes vegetable and seed oils such as soybean oil, canola oil, safflower oil, sunflower oil, peanut oil, and rapeseed oil. Limit intake of PUFA-rich foods like nuts, seeds, fatty fish, fatty poultry, and fatty pork. Cut out fish oil supplementation and strive to limit PUFA intake, especially when eating out.
  2. Increase intake of saturated fats: Staple sources of saturated fats include coconut oil, butter, ghee, cream, and beef fat. These can be easily used for cooking or added to any hot meal.
  3. Minimize monounsaturated fats: Olive oil, macadamia nuts, and avocados are the major sources of monounsaturated fats. They should be used sparingly and not cooked with, as cooking with them can lead to oxidation.
  4. Include more short- and medium-chain fats: Consuming more of these fats, such as those found in coconut oil, may provide potential metabolic and health benefits.
  5. Initially, aim for approximately 1/3rd  of total calorie intake to come from fat to aid in PUFA detoxification: Adjusting your fat intake can help your body slowly get rid of stored PUFAs while preventing negative side effects.


the thermo diet




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    Other potential useful references


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    • Raederstorff D, Wyss A, Calder PC, Weber P, Eggersdorfer M. Vitamin E function and requirements in relation to PUFA. Br J Nutr. 2015;114(8):1113-1122. doi:10.1017/S000711451500272X